I-Evolution yeeNgcebiso zePipette: Uhambo lokuTshintsha
Iingcebiso zePipetteziye zaba sisixhobo esibalulekileyo kwizicwangciso zaselabhoratri, ezivumela ukuphatha ulwelo oluchanekileyo kuphando lwezenzululwazi, uxilongo, kunye nezicelo ezahlukeneyo zemizi-mveliso. Ukutyhubela iminyaka, ezi zixhobo zilula zitshintshile kakhulu. Olu tshintsho lubangelwa iteknoloji entsha, izixhobo ezingcono, kunye nesidingo sokuchaneka kwiindawo ezixakekileyo.
Eli nqaku lijonga indlela iingcebiso zepipette eziye zaphuhliswa ngayo. Iquka iziqalo zabo ezilula ekusebenzeni kwabo okuphezulu namhlanje. Olu tshintsho luye lwabumba umsebenzi wenzululwazi wale mihla.
Iintsuku zokuQala zokuphatha ulwelo: iiPipettes zeManuwali kunye nokulinganiselwa kwazo
Kwinqanaba lokuqala lophando lwebhubhoratri, izazinzulu zasebenzisa i-pipettes manual yokudluliselwa kwamanzi. Amagcisa ayedla ngokwenza ezi zixhobo zilula zeglasi. Babekwazi ukuhambisa ulwelo ngokuchanekileyo, kodwa izandla ezinobuchule kwakufuneka ziqinisekise ukuchaneka. Nangona kunjalo, imida yayibonakala - babetyekele kwimpazamo yomsebenzisi, ungcoliseko, kunye nokungahambelani kwimiqulu yolwelo.
Ukusetyenziswa kweengcebiso ezilahlayo kwi-pipettes ye-manual yayingaqhelekanga kwizigaba zokuqala. Iingcali zenzululwazi ziya kuhlambulula kwaye ziphinde zisebenzise iipayipi zeglasi, eziye zandisa umngcipheko wokungcola kunye nokulahleka kwesampulu. Isidingo sezisombululo ezithembeke ngakumbi nezicocekileyo kwiilabhoratri, ngakumbi njengoko imiqulu yophando ikhula, yaya icaca ngakumbi.
Ukuvela koKulahlwaIingcebiso zePipette
Impumelelo yokwenyani kwitekhnoloji yepipette yeza nokuqaliswa kweengcebiso zepipette ezilahlwayo kwiminyaka yoo-1960 kunye neyee-1970. Abavelisi baqale bazenza ezi zinto ngezinto zeplastiki ezingabizi kakhulu kunye nekhemikhali ezifana ne-polystyrene kunye ne-polyethylene.
Iingcebiso ezilahlayo zineenzuzo ezininzi xa kuthelekiswa neepayipi zeglasi. Banceda ukuthintela ukungcoliseka phakathi kweesampuli. Zikwasusa nemfuneko yokuvala inzala etya ixesha.
Abantu bayila ezi ngcebiso zakuqala ezilahlwayo kwiipipettes ababezisebenza ngesandla. Ukuzisebenzisa kwakusafuna umgudu omkhulu. Ukukwazi ukubuyisela lula ingcebiso emva kokusetyenziswa kwanceda abaphandi bagcina iisampuli zikhuselekile. Oku kukwaphucule nesantya somsebenzi elebhu.
Ukungeniswa kweeNkqubo zokuPhathwa koLwalo oluSebenzayo
Njengoko uphando lwezenzululwazi luqhubela phambili, iilabhoratri ziye zagxila ngakumbi ekwandiseni iziphumo kunye nokunciphisa iimpazamo zabantu. Ngoo-1980 kunye no-1990, iinkqubo zokuphatha ulwelo oluzenzekelayo lwaqala ukubonakala. Oku kwaba ngenxa yokukhula kwemfuno yovavanyo lokuphumelela okuphezulu. Ezi nkqubo zazibalulekile kwi-genomics, uphando lwamayeza, kunye noxilongo.
Ezi nkqubo zenze ukuba kudluliselwe ulwelo olukhawulezayo noluchanekileyo kwiipleyiti ezinamaqula amaninzi. Oku kubandakanya iipleyiti ezingama-96 kunye namaqula angama-384. Bakwenza oku ngaphandle kokufuna uncedo oluthe ngqo lomntu.
Ukunyuka kweenkqubo zemibhobho ezizenzekelayo zenze imfuno yeengcebiso ezikhethekileyo zepayipi. La macebiso anceda iirobhothi okanye oomatshini. Ngokungafaniyo neepipettes zemveli, ezi nkqubo ezizenzekelayo zifuna iingcebiso ezihambelana ngokuchanekileyo. Zikwafuna iindlela zokuncamathela ezikhuselekileyo kunye neempawu zokugcina eziphantsi.
Oku kunceda ukunciphisa ilahleko yesampulu kwaye kuthintele ukungcoliseka komnqamlezo. Oku kwakhokelela ekudalweni kweengcebiso ze-robotic pipette. Abantu bahlala bebiza ezi ngcebiso "LiHa" iingcebiso. Iinjineli ziyila ukuze zilingane iinkqubo ezithile zerobhothi ezifana neerobhothi zeTecan kunye neHamilton.
Ukuqhubela phambili kwizinto zoMathiriyeli kunye noYilo: Ukusuka ekugcinweni okuphantsi ukuya kwi-Ultra-Precision
Ngokuhamba kwexesha, uyilo kunye nezinto ezisetyenziselwa iingcebiso zepipette zavela ukuhlangabezana neemfuno ezikhulayo zophando lwezenzululwazi. Iingcebiso zeplastiki zakuqala, nangona zifikeleleka, azizange zihlale zisenza ngcono ukusebenza.
Iilebhu zophando ziqalise ukucela iingcebiso ezinciphisa ukugcinwa kwesampulu. Oku kuthetha ukuba abasebenzisi bashiya ulwelo oluncinci kwincam emva kokusetyenziswa. Kwakhona bafuna iingcebiso ezinokumelana nekhemikhali engcono.
Abavelisi ngokuqhelekileyo benza iingcebiso ze-pipette zanamhlanje ezivela kwi-polypropylene ephezulu (PP). Abaphandi bayazi le nto ngokuzinza kweekhemikhali. Ikwamelana nobushushu kwaye inciphisa ukugcinwa kolwelo.
Ukuveliswa kwezinto ezintsha ezifana neTekhnoloji yokugcinwa okuphantsi kwavela, kunye neengcebiso ezenzelwe ukuthintela ulwelo ukuba ubambelele kumphezulu ongaphakathi. Iingcebiso zePipette zilungile kwimisebenzi efuna ukuphatha ngononophelo ulwelo. Oku kubandakanya i-PCR, inkcubeko yeeseli, kunye novavanyo lwe-enzyme. Nokuba ilahleko encinci yesampulu inokuchaphazela iziphumo.
Itekhnoloji yeClipTip, ebonelela ngokhuseleko, uncamathiselo oluvuzayo kwiipipettes, yenye yenkqubela phambili yamva nje. Olu tshintsho lugcina iingcebiso ngokukhuselekileyo zincanyathiselwe ngelixa zisetyenziswa. Oku kuthintela ukukhuselwa ngengozi okunokubangela ungcoliseko lwesampulu.
Ukufaneleka okukhuselekileyo kubaluleke kakhulu kwimisebenzi ephezulu, njenge-384-well plate assays. Le misebenzi idinga ukuphathwa ngokukhawuleza kolwelo kunye nokuchaneka ngenxa ye-automation.
Ukunyuka kweeNgcebiso zePipette eziZodwa
Njengoko iinkalo ezahlukeneyo zenzululwazi ziye zahambela phambili, ngokunjalo kufuneka neemfuneko zeengcebiso ze-pipette. Namhlanje, kukho iingcebiso ezikhethekileyo ezenzelwe ukusetyenziswa ezahlukeneyo. Nazi ezinye iintlobo zeengcebiso:
- Iingcebiso zefomathi ezingama-384
- Iingcebiso zokucoca ukuthintela ukungcoliseka kweaerosol
- Iingcebiso ezibophelelayo eziphantsi ze-DNA okanye i-RNA
- Iingcebiso zeRobhothi zeenkqubo zokuphatha ulwelo oluzenzekelayo
Ngokomzekelo, iingcebiso ze-pipette zokucoca zinefifa encinci. Esi sihluzo sinqanda ii-aerosols kunye nezingcolisi ukuba zingahambi phakathi kweesampuli. Inceda ukugcina iisampulu zinyulu kumsebenzi webhayoloji obuthathaka.
Iingcebiso ezibophelelayo eziphantsi zinonyango olukhethekileyo lomphezulu. Olu nyango lumisa iimolekyuli zebhayoloji, njengeDNA okanye iiproteni, ukuba zingabambeleli ngaphakathi kwincam. Olu phawu lubaluleke kakhulu kumsebenzi webhayoloji yemolekyuli.
Ngokunyuka kwe-lab automation, abavelisi baqulunqa iingcebiso ze-pipette ukuze basebenze kakuhle kunye neenkqubo eziphezulu. Ezi nkqubo ziquka i-Thermo Scientific, i-Eppendorf, kunye namaqonga e-Tecan. Ezi ngcebiso zingenamthungo kwiinkqubo zerobhothi zokuhanjiswa kolwelo oluzenzekelayo, ukuphucula ukusebenza kakuhle, ukuchaneka, kunye nokungaguquguquki kwiindlela ezahlukeneyo zokusebenza zaselabhoratri.
Ukuzinza kuPhuhliso lweNgcebiso yePipette
Njengezinye izixhobo ezininzi zelebhu, kukho ukugxila okukhulayo ekuzinzeni ekwenzeni iingcebiso ze-pipette. Iinkampani ezininzi zizama ukusombulula iingxaki ezibangelwa kukusetyenziswa kweplastiki enye. Baphonononga i-biodegradable, i-reusable, okanye ukhetho oluzinzileyo kwiingcebiso ze-pipette. Ezi ngcebiso zinceda ukunciphisa inkunkuma ngelixa ugcina ukusebenza okuphezulu kunye nokuchaneka okufunekayo kuphando lwangoku.
Olunye uphuculo lubandakanya iingcebiso abasebenzisi abanokucoca kwaye baphinde basebenzise amaxesha amaninzi ngaphandle kokulahleka kokusebenza. Kukwakho neenzame zokuthoba umgangatho wekhabhoni wokuvelisa.
Ikamva leengcebiso zePipette
Ikamva leengcebiso zepipette lixhomekeke ekuphuculeni izinto, ukuyila kunye neempawu. Olu tshintsho luya kwandisa ukusebenza kwabo, ukusebenza kakuhle, kunye nokuzinza. Njengoko iilebhu zifuna ukuchaneka ngakumbi kunye nokuthembeka, iingcebiso ezihlakaniphile ziya kuxhaphaka ngakumbi. Ezi ngcebiso zinokulandela umthamo wolwelo kunye nokubeka iliso kusetyenziso ngexesha lokwenyani.
Ngokukhula kweyeza lomntu, ukuxilongwa kwe-point-of-care, kunye nenkqubela phambili ye-biotech, iingcebiso ze-pipette ziya kuhlala zitshintsha. Baya kuziqhelanisa neemfuno zale mihlaba.
Iingcebiso zePipette ziye zahamba indlela ende. Baqala njengeepayipi zeglasi ezilula. Ngoku, sisebenzisa iingcebiso eziphambili kunye nezikhethekileyo.
Olu tshintsho lubonisa indlela uphando lwebhubhoratri kunye nobuchwepheshe obuphuculwe ngayo ngokuhamba kwexesha. Njengoko uphando lufuna ukukhula, ngokunjalo nesidingo sokuchaneka, ukuthembeka, kunye nokusebenza kakuhle ekuphatheni ulwelo. Ukuphuhliswa kwezi zixhobo kuya kuhlala kudlala indima ebalulekileyo. Baza kunceda ukuqhubela phambili imimandla efana nebhayoloji yemolekyuli, ukufunyanwa kweziyobisi, kunye noxilongo.
At Ace Biomedical, Siyazingca ngokubonelela ngeengcebiso eziphezulu zepipette. Iingcebiso zethu zinceda ukuxhasa impumelelo entsha yenzululwazi kwaye negalelo kwimpumelelo yelabhu yakho.
Ngolwazi oluthe vetshe malunga neemveliso kunye neenkonzo zethu, ndwendwela iphepha lethu lasekhaya. Ukuba unomdla ekuphononongeni izinto ezithile, jonga yethuIimvelisoor Qhagamshelana nathi.
Ixesha lokuposa: Dec-24-2024