Chii chinonzi in vitro diagnosis?

In vitro diagnostics inoreva maitiro ekuongorora chirwere kana mamiriro nekuisa mumapoka ebiological samples kubva kunze kwemuviri. Iyi nzira inotsamira zvakanyanya pane dzakasiyana siyana mamorekuru biology nzira, kusanganisira PCR uye nucleic acid kubviswa. Pamusoro pezvo, kubata kwemvura chinhu chakakosha che in vitro diagnostics.

PCR kana polymerase chain reaction inzira inoshandiswa kukudza zvidimbu zveDNA. Nekushandisa maprimers chaiwo, PCR inobvumira kukwidziridzwa kwakasarudzika kweDNA sequences, iyo inogona kuongororwa zviratidzo zvechirwere kana hutachiona. PCR inowanzoshandiswa kuona zvirwere zvehutachiona, bhakitiriya, fungal uye parasitic, pamwe nezvirwere zvemajini uye kenza.

Nucleic acid extraction inzira inoshandiswa kupatsanura uye kuchenesa DNA kana RNA kubva kubiological samples. Iwo akabviswa nucleic acids anobva awanikwa kuti awedzere kuongororwa, kusanganisira PCR. Nucleic acid kubviswa kwakakosha pakuongororwa uye kuronga kurapwa kwezvirwere zvakasiyana uye mamiriro.

Mabatirwo ezvinwiwa inzira inosanganisira kunyatsofambiswa, kugovera nekusanganiswa kwezvinwiwa zvidiki munzvimbo yerabhoritari. Automated liquid inobata masisitimu ave kuwedzera kukurumbira mumakore achangopfuura sezvo achigonesa kukwirira kwepamusoro uye kunyatsoita muyedzo akadai sePCR uye nucleic acid kubviswa.

In vitro diagnostics inotsamira zvakanyanya pane aya mamorekuru biology matekiniki nekuti anotendera kutariswa uye kuongororwa kwechirwere-chinosanganisirwa genetic uye molecular mamaki. Semuyenzaniso, PCR inogona kushandiswa kukwidziridza kutevedzana kwemajini ane chekuita negomarara rezamu, nepo nucleic acid inotorwa inogona kushandiswa kupatsanura bundu-inotorwa DNA kubva kuropa samples.

Pamusoro peaya matekiniki, mamwe akasiyana matekiniki nemidziyo inoshandiswa mu in vitro diagnostics. Semuenzaniso, michina yemicrofluidic iri kuwedzera kushandiswa mune yakakwirira-kuburikidza uye point-ye-care application. Zvishandiso izvi zvakagadzirirwa kunyatso kubata uye kushandisa zvinwiwa zvidiki, zvichiita kuti zvive zvakanakira PCR uye mamwe mamorekuru biology application.

Saizvozvo, chizvarwa chinotevera sequencing (NGS) matekinoroji ari kutamba inowedzera kukosha mu in vitro diagnostics. NGS inogonesa kutevedzana kwakafanana kwemamiriyoni ezvimedu zveDNA, zvichiita kuti kurumidze uye kwakaringana kuonekwa kwechirwere-chakabatana nemajini ekuchinja. NGS ine mukana wekushandura kuongororwa uye kurapwa kwezvirwere zvemajini negomarara.

Muchidimbu, in vitro diagnostics chikamu chakakosha chemushonga wemazuva ano uye unovimba zvakanyanya nemamolekyulu biology matekiniki akadai sePCR, nucleic acid kudhirowa, uye kubata kwemvura. Idzi matekinoroji, pamwe chete nehunyanzvi hwakadai semicrofluidic zvishandiso neNGS, zviri kushandura nzira yatinoongorora nekurapa nayo chirwere. Sezvo tekinoroji ichienderera mberi, in vitro diagnostics ingangove yakanyatsojeka uye inoshanda, pakupedzisira inovandudza mhedzisiro yemurwere uye hupenyu hwehupenyu.

At Suzhou Ace Biomedical,isu takazvipira kukupa iwe yemhando yepamusoro yelab zvekushandisa kune zvese zvaunoda zvesainzi. Yedu yemhando yepipette matipi, PCR mahwendefa, PCR machubhu, uye yekuisa chisimbiso firimu zvakagadzirirwa zvine hungwaru uye kugadzirwa kuti ive nechokwadi uye huchokwadi mune zvese zviedzo zvako. Mazano edu epipette anowirirana nemhando dzose huru dzepipette uye anouya mumhando dzakasiyana-siyana kuti aenderane nezvido zvako. Yedu PCR mahwendefa uye machubhu anogadzirwa kubva emhando yepamusoro zvinhu uye akagadzirirwa kutsungirira akawanda ekupisa kutenderera uku uchichengetedza kuvimbika kwemuenzaniso. Yedu yekuisa chisimbiso firimu inopa chisimbiso chakasimba kudzivirira evaporation uye kusvibiswa kubva kunze kwezvinhu. Isu tinonzwisisa kukosha kweakavimbika uye anoshanda lab ekushandisa, ndosaka tichiyedza kukupa iwe zvigadzirwa zvemhando yepamusoro uye masevhisi anogoneka. Chikwata chedu chenyanzvi chinogara chiripo kuti chikubatsire iwe chero mibvunzo kana zvinokunetsa zvaungave nazvo.

Basa reLab-Yakagadziridzwa Miedzo muIn Vitro Diagnostics Market | Pew Charitable Trusts

 


Nguva yekutumira: May-10-2023