Iyo yakazvininipisa pipette tipi idiki, yakachipa, uye yakakosha kusainzi. Inopa simba kutsvagisa mumishonga mitsva, Covid-19 diagnostics, uye ongororo yese yeropa yakambomhanya.
Izvo zvakare, kazhinji, zvakawandisa - akajairwa bhenji sainzi anogona kubata gumi nemaviri zuva rega rega.
Asi ikozvino, nhevedzano yekutyora-nguva isina kurongeka padyo nepipette tip yekugovera cheni - inokurudzirwa nekudzima, moto, uye denda rine chekuita nedenda - rakagadzira kushomeka kwepasirese kuri kutyisidzira ingangoita makona ese enyika yesainzi.
Kushaikwa kwepipette tip kuri kutoisa mungozi zvirongwa munyika yose zvinoongorora vacheche vacheche mamiriro ezvinhu anogona kuuraya, sekutadza kugaya shuga mumukaka wezamu. Zviri kutyisidzira kuedza kwemayunivhesiti pa stem cell genetics. Uye iri kumanikidza makambani ebiotech ari kushanda kugadzira mishonga mitsva kuti afunge kuisa mberi kumwe kuedzwa pamusoro pevamwe.
Parizvino, hapana chiratidzo chekuti kushomeka kuchapera munguva pfupi - uye kana zvikawedzera, masayendisiti anogona kutanga kumisa kuyedza kana kusiya zvimwe zvebasa ravo.
Pamasayendisiti ose asingatyiswi nekushomeka uku, vatsvakurudzi vane basa rekuongorora vacheche ndivo vakanyanya kurongeka uye vanotaura pachena.
Marabhoritari ehutano hweveruzhinji anovheneka vacheche mukati memaawa ekuzvarwa kwavo kune akawanda emajini mamiriro. Zvimwe, senge phenylketonuria uye kushomeka kweMCAD, zvinoda kuti vanachiremba vachinje machengetero avari kuita mwana. Kunyangwe kungononoka muchirongwa chekuongorora kwakakonzera kufa kwevamwe vacheche, maererano neongororo ya2013.
Kuongororwa kwemwana wega wega kunoda matipi epipetti makumi matatu kusvika makumi mana kuti apedze makumi ebvunzo dzekuongorora, uye zviuru zvevana zvinozvarwa zuva rega rega muUnited States.
Kutanga muna Kukadzi, maLab aya aiburitsa pachena kuti vaive vasina zvekushandisa. MaLab mumatunhu gumi nemana ane matipi epipette asingasviki mwedzi asara, sekureva kweSangano rePublic Health Laboratories. Boka iri rainetsekana zvekuti, kwemwedzi yakati, rakamanikidza hurumende yemubatanidzwa - kusanganisira iyo White House - kukoshesa zvinodiwa nepipette yezvirongwa zvekuongorora vachangozvarwa. Kusvika pari zvino, sangano iri rinoti, hapana chachinja; White House yakaudza STAT kuti hurumende iri kushanda munzira dzinoverengeka dzekuwedzera kuwanikwa kwemazano.
Mune dzimwe nzvimbo, kushomeka kwemapurasitiki "kwakada kuita kuti zvikamu zvezvirongwa zvekuvheneka vana vachangozvarwa zvivharwe," akadaro Susan Tanksley, maneja webazi muchikamu chebazi rezvehutano muLabhoritari yebazi reTexas, pamusangano waFebruary wedare rinopa mazano rekuongororwa kwevachangozvarwa. . (Tankskey uye dhipatimendi rezvehutano rehurumende havana kupindura kuchikumbiro chekutaura.)
Dzimwe nyika dziri kugamuchira matipi ematipi kwasara zuva rimwe chete kuti vasara, zvichivasiya vasina sarudzo kunze kwekukumbira mamwe maLab kuti achengetedze, sekureva kwaScott Shone, director weNorth Carolina's state health laboratory. Shone akati akanzwa nezvevamwe vakuru vezvehutano vachifona “vachiti, 'Ndiri kukurumidza kubuda mangwana, mungagona kundiraramisa chimwe chinhu here?' Nokuti mutengesi anoti ichauya, asi ini handizivi.’”
"Kuvimba kana mutengesi achiti, 'Mazuva matatu usati wapera, tichakutorera imwe mwedzi' - kunetseka," akadaro.
MaLab mazhinji akatendeukira kune dzimwe nzira dzakabirwa nejury. Vamwe vari kuwacha matipi vobva vaashandisa zvakare, zvichiwedzera njodzi inogona kuitika yekutapukirwa. Vamwe vari kumhanyisa vachangobva kuzvarwa screenings mumabhechi, izvo zvinogona kuwedzera nguva inotora kuunza mhedzisiro.
Kusvika pari zvino, zvigadziriso izvi zvave zvakakwana. "Hatisi mumamiriro ezvinhu apo kune ngozi yekukurumidza kuvana vachangoberekwa," Shone akawedzera.
Kupfuura marabhoritari anovheneka vana vachangozvarwa, makambani ebiotech anoshanda pakurapa kutsva uye marabhoritari emayunivhesiti ari kuita tsvakiridzo yekutanga ari kunzwawo kusvinwa.
Masayendisiti kuPRA Health Sayenzi, sangano rekutsvagisa kondirakiti iro riri kushanda mukuyedzwa kwekiriniki yehepatitis B uye vakati wandei Bristol Myers Squibb vanotora zvinodhaka, vanoti zvekushandisa zvinopera idambudziko rinogara riripo - kunyangwe vanga vasati vanonoka kuverenga.
"Dzimwe nguva, zvinosvika kune rimwe rack remazano rakagara pasherufu yekumashure, uye isu takaita senge 'Ah Mwari wangu," akadaro Jason Neat, director director webioanalytical services paPRA Health's lab muKansas.
Kuperevedza kwave kutyisa zvakakwana kuArrakis Therapeutics, kambani yeWaltham, Mass. inoshanda pakurapwa kwegomarara, mamiriro etsinga, uye zvirwere zvisingawanzo, izvo mukuru weRNA biology, Kathleen McGinness, akagadzira yakazvitsaurira Slack chiteshi kubatsira vamwe vake kugovana. mhinduro dzekuchengetedza pipette mazano.
"Takaziva kuti izvi hazvina kuomarara," akadaro nezve chiteshi, #tipsfortips. "Chikwata chizhinji chave chakasimba nezvemhinduro, asi isu takanga tisina nzvimbo yepakati yekugovera izvozvo."
Mazhinji emakambani ebiotech akabvunzurudzwa neSTAT akati vari kutora matanho ekuchengetedza mapipette mashoma uye, kusvika parizvino, havasati vamisa basa.
Masayendisiti aOctant, semuenzaniso, ari kunyanya kusarudza nezve kushandisa yakasefa pipette matipi. Aya matipi - ayo akanyanya kunetsa kuwana nguva pfupi yadarika - anopa samples imwe dura redziviriro kubva kune kunze zvinosvibisa, asi haigone kucheneswa uye kushandiswa zvakare. Saka vanenge vachivakumikidza kuzviitwa zvinonyanya kunetsa.
"Kana usiri kuterera kune zviri kupera, unogona kupera zvinhu zviri nyore," akadaro Danielle de Jong, maneja werabhu paYunivhesiti yeFlorida's Whitney Laboratory; iyo lab yaanoshanda muzvidzidzo mashandiro anoita maseru masero mumhuka diki dzemugungwa dzine hukama nejellyfish dzinogona kuzvigadzira patsva zvikamu zvadzo.
Masayendisiti paWhitney Laboratory, pane dzimwe nguva, akabvisa vavakidzani vavo apo maodha ekupa haana kusvika nenguva; de Jong akatozvibata achitarisa mamwe masherufu emalabhu kune chero asina kushandiswa pipette matipi, kungoitira kana lab yake ichida kukwereta.
“Ndave ndichishanda murabhoritari kwemakore 21,” akadaro. “Handisati ndambosangana nenyaya dzekutengesera dzakadai. Nguva dzose.”
Hapana imwe tsananguro yekushomeka uku.
Kamwe kamwe kuputika kweCovid-19 bvunzo gore rapfuura - imwe neimwe inotsamira pamapipette matipi - zvirokwazvo yakaita basa. Asi mhedzisiro yenjodzi dzinongoitika dzoga uye dzimwe tsaona dzinotyisa dzinowedzera kumusoro kwekutengesa dzakadzikawo kumabhenji erabhoritari.
Kudzimwa kwemagetsi munyika yose muTexas, uko kwakauraya vanhu vanopfuura zana, kwakatyorawo chinongedzo chakakomba mune yakaoma pipette yekugovera cheni. Kudzimwa kwemagetsi uku kwakamanikidza ExxonMobil nemamwe makambani kuvhara zvidyarwa mudunhu kwenguva - mamwe acho akagadzira polypropylene resin, iyo mbishi yemapipetti matipi.
Zvinoenderana nemharidzo yaKurume, ExxonMobil's Houston-nzvimbo chirimwa yaive kambani yechipiri pakukura mugadziri we polypropylene muna 2020; chete chirimwa chayo chekuSingapore chakagadzira zvimwe. Zviviri zveExxonMobil's matatu makuru e polyethylene zvirimwa zvaive zvakare muTexas. (Muna Kubvumbi 2020, ExxonMobil yakatowedzera kugadzirwa kwepolypropylene pazvidyarwa zviviri zveUS-based.)
“Mushure medutu rechando muna Kukadzi gore rino, zvinofungidzirwa kuti chikamu chinodarika 85% chepolypropylene kugadzirwa muUS chakakanganisika nekuda kwenyaya dzakasiyana siyana dzakadambuka mapombi panzvimbo dzekugadzira pamwe nekurasikirwa kwemagetsi nemagetsi. zvakakosha zvekushandisa zvinodikanwa kutangazve kugadzira, "akadaro mutauriri weTotal, imwe kambani yemafuta negasi yeHouston inogadzira polypropylene.
Asi cheni dzekugovera dzakasimbiswa kubva zhizha rapfuura - nguva yaFebruary isati yanyanya kutonhora. Yakaderera-kupfuura-yakajairwa huwandu hwemidziyo haisiriyo yega chinhu chiri kutenderedza cheni dzekugovera - uye matipi epipette handiyo yega chidimbu chepurasitiki-chigadzirwa chelab giya chave kushomeka.
Moto wekugadzira chirimwa wakabvisawo makumi masere muzana muzana ekupihwa kwenyika kwemidziyo yemapipette akashandiswa uye zvimwe zvinhu zvakapinza, sekureva kwegwaro rakatumirwa pawebhusaiti yeYunivhesiti yePittsburgh.
Uye muna Chikunguru, US Customs uye Border Dziviriro yakatanga kuvharira zvigadzirwa kubva kune yakakura magirovhosi aifungidzirwa maitiro ekumanikidzirwa ekushanda. (CBP yakabudisa zvakawanikwa pakuferefeta kwayo mwedzi wapera.)
"Zvatiri kuona ichokwadi chero chinhu chiri muplastic-ine chekuita nedivi rebhizinesi - polypropylene, kunyanya - ingave iri kumashure, kana iri kudiwa zvakanyanya," akadaro PRA Health Sayenzi 'Neat.
Kudiwa kwacho kwakakwira zvekuti mutengo wezvimwe zvinhu zvinoshomeka wakakwira, sekureva kwaTiffany Harmon, maneja wezvekutenga zvinhu paPRA Health Sayenzi 'bioanalytics lab muKansas.
Iyo kambani ikozvino yave kubhadhara 300% yakawanda yegirovhosi kuburikidza neayo anogara achitengesa. Uye PRA's pipette tip mirairo ikozvino ine imwe mubhadharo wakaiswa pairi. Imwe mugadziri wepipette tip, iyo yakazivisa kubhadharisa kutsva kwe4.75% mwedzi wapera, yakaudza vatengi vayo kuti danho iri rakakosha nekuti mutengo wemidziyo yepurasitiki yakada kupeta zvakapetwa kaviri.
Chinowedzera kusava nechokwadi kwemasayendisiti emurabhoritari inzira yevanogovera yekuona kuti ndeapi maodha anotanga kuzadzwa - mashandiro ayo masayendisiti mashoma akati ainyatsonzwisisa.
"Nharaunda yevashandi yanga ichibvunza kubva pakutanga kuti itibatsire kunzwisisa kuti sarudzo idzi dzinoitwa sei," akadaro Shone, uyo akataura nezvemafomu evatengesi ekuona kugoverwa se "black box magic."
STAT yakabata makambani anopfuura gumi nemaviri anogadzira kana kutengesa matipi epipette, anosanganisira Corning, Eppendorf, Fisher Scientific, VWR, uye Rainin. Vaviri chete vakapindura.
Corning akaramba kutaura, achitaura zvibvumirano zvevaridzi nevatengi vayo. MilliporeSigma, zvakadaro, yakataura kuti inogovera pipettes pane yekutanga-kuuya, yekutanga-serve base.
"Kubva pakatanga denda, indasitiri yesainzi yehupenyu yakaona kudiwa kusati kwamboitika kwezvigadzirwa zvine chekuita neCovid-19, zvinosanganisira MilliporeSigma," mutauriri wekambani huru yekugovera zvesainzi akaudza STAT mune email. "Tiri kushanda 24/7 kusangana nekuwedzera uku kudiwa kwezvinhu izvi uye pamwe neizvo zvinoshandiswa mukuwanikwa kwesainzi."
Pasinei nekuedza kusimbisa ketani yekugovera, hazvisi pachena kuti kushomeka kuchagara kwenguva yakareba sei.
Corning yakagamuchira madhora gumi nemashanu kubva kuDhipatimendi reDziviriro kuti iite 684 miriyoni mamwe matipi epipette pagore panzvimbo yayo muDurham, NC Tecan, zvakare, iri kuvaka zvivakwa zvitsva zvekugadzira nemadhora makumi matatu nemaviri emamiriyoni kubva kuCARES Act.
Asi izvo hazvigadzirise dambudziko kana kugadzirwa kwepurasitiki kukaramba kwakaderera pane zvaitarisirwa. Uye hapana wemapurojekiti iwayo achanyatso kuburitsa matipi epipette kusati kwadonha kwa2021, zvakadaro.
Kusvika panguva iyoyo, mamaneja emarabhoritari nemasainzi vari kutsvaga kushomeka kwepipette uye chero chimwe chinhu.
“Takatanga denda iri tisina maswabs nemedia. Uye ipapo takava nekushomeka kwemareagents. Zvino takava nekushomeka kwemapurasitiki. Zvino takave nekushomeka kwemareagents zvakare, ”akadaro Shone wekuNorth Carolina. "Zvakafanana neZuva reGroundhog."
Nguva yekutumira: Feb-12-2022