Yuav Ua Li Cas Xaiv Txoj Cai Liquid Handling Automation Platform

Tsis siv neeg pipetingyog ib txoj hauv kev ua tau zoo tshaj plaws los txo tib neeg kev ua yuam kev, ua kom muaj tseeb thiab raug, thiab ua kom lub chaw ua haujlwm hauv chav kuaj. Txawm li cas los xij, kev txiav txim siab ntawm "yuav tsum-muaj" cov khoom siv rau kev ua haujlwm tau zoo automation kua tuav yog nyob ntawm koj lub hom phiaj thiab kev siv. Kab lus no tham txog qee cov ntsiab lus tseem ceeb los txiav txim siab thaum xaiv lub tshuab ua kua rau koj lub chaw kuaj.

Automating pipetting yog ib kauj ruam tseem ceeb hauv kev txhim kho kev ua haujlwm hauv chav kuaj, pab ua kom rov tsim dua tshiab, txhawb kev xa tawm, thiab txo qhov yuam kev. Cov chaw soj nstuam nyob ntawm cov cuab yeej siv ua kua ua kua rau ntau hom kev siv, suav nrog kev npaj ua qauv, kev rho tawm DNA, kev soj ntsuam ntawm tes, thiab ELISAs. Cov platforms no yog kev nqis peev mus sij hawm ntev thiab yuav tsum tau xaiv tsis yog raws li cov kev xav tau niaj hnub no, tab sis kuj yog cov kev xav tau yav tom ntej ntawm chav kuaj. Qhov no yuav xyuas kom meej tias lub platform raug xaiv, thiab tuaj yeem ua haujlwm tau zoo hauv chav kuaj rau ntau xyoo tom ntej.

Thawj kauj ruam

Ua ntej txiav txim siab, ua tib zoo saib cov txheej txheem kom ua haujlwm:

Puas yog koj pib nrog cov txheej txheem muaj zog?

Kua tuav automation tuaj yeem txhim kho kev ua haujlwm ntawm phau ntawv, tab sis nws tsis tuaj yeem kho qhov kev ntsuas uas tsis tau ua haujlwm. Txiav koj qhov kev ua haujlwm mus rau hauv tus kheej cov kauj ruam, thiab xav txog qhov muaj feem cuam tshuam ntawm txhua tus ntawm kev ua haujlwm tag nrho. Piv txwv li, kev soj ntsuam los ntawm ib tug manually pipetted, raj-raws li hom ntawv mus rau ib tug automated, siab dua-density, phaj-raws li workflow txhais tau hais tias cov qauv thiab reagents yuav nyob rau hauv lub lawj rau lub sij hawm ntev dua. Qhov no yuav cuam tshuam li cas rau kev ncaj ncees ntawm koj cov qauv thiab cov tshuaj reagents?

Koj cov kev xav tau yuav hloov li cas?

Txhawm rau txuag nyiaj, nws yuav yog kev ntxias kom nqis peev rau hauv ib qho system uas tsuas yog ua tau raws li koj qhov chaw kuaj xav tau tam sim no, tab sis nyob rau lub sijhawm ntev koj tuaj yeem poob. Xav txog cov ntsiab lus tseem ceeb, thiab qhov twg yuav zoo rau muaj. Ib qho zoo automated kua tuav system yuav tsum reconfigurable yog li ntawd koj muaj peev xwm coj nyob rau hauv daim ntawv thov tshiab thiab workflows raws li xav tau kev hloov. Nrog rau qhov hloov tau yooj yim, modular system, ntau lub ntsiab lus ntawm koj cov haujlwm tam sim no tuaj yeem rov ua dua thiab hloov kho dua tshiab.

Puas muaj qhov kev daws teeb meem sab nraud uas ua tau raws li koj xav tau?

Qee qhov chaw ua haujlwm tshwj xeeb tau ua kom zoo rau cov ntawv thov tshwj xeeb nrog cov txheej txheem pov thawj, xws li kev rho tawm DNA, kev npaj ua qauv, thiab kab lis kev cai ntawm tes. Qhov no tuaj yeem ua kom yooj yim rau koj cov txheej txheem xaiv, thiab tseem muab cov "core" tseem ceeb rau kev koom ua ke rau hauv cov kab ke loj dua yav tom ntej. Off-the-shelf kev daws teeb meem tsim nrog rau yav tom ntej kev koom ua ke thiab hloov tau yooj yim hauv siab yog qhov zoo dua rau kev hloov pauv tsis tau, "kaw" platforms.

Koj muaj chaw ntau npaum li cas, thiab koj puas siv nws zoo?

Qhov chaw feem ntau yog cov khoom muaj nqis heev. Feem ntau cov khoom siv ua kua tam sim no muaj ntau tus neeg siv, uas tau nce qhov kev thov kom yooj yim thiab siv qhov chaw tshiab. Xav txog kev xaiv lub tshuab ua haujlwm uas tuaj yeem nkag mus rau qhov chaw hauv qab ntawm lub rooj ua haujlwm kom ncav cuag, piv txwv li, kev tshuaj xyuas ntxiv lossis cov qauv npaj cov khoom siv, thiab lwm yam.

Nws yooj yim npaum li cas rau kev tswj thiab kev pabcuam?

Tsis txhob saib xyuas kev pabcuam thiab kev saib xyuas. Kev yooj yim ntawm kev nkag los ntawm cov kws tshaj lij tuaj yeem txo qis sijhawm thiab cuam tshuam rau koj qhov kev ua haujlwm.

Xaiv qhov kho vajtse zoo

Txawm hais tias koj tab tom ua haujlwm hauv genomics, cell biology, kev tshawb nrhiav tshuaj, kev kuaj mob molecular, lossis ib yam dab tsi txawv kiag li, txoj cai tswj cov kua dej yuav ua rau koj lub neej yooj yim dua. Cov ntsiab lus tseem ceeb suav nrog:

Cua los yog kua displacement pipeting?

Kev hloov pauv huab cua yog qhov zoo tshaj plaws rau kev xa tawm ntau qhov ntim ntau, ntawm 0.5 txog 1,000 μL. Txawm hais tias tsuas yog siv tau nrog cov lus qhia pov tseg, qhov no ua rau kom nrawm thiab tsim tau los ntawm kev tshem tawm cov kauj ruam ntxiv cuam tshuam nrog cov kua xaim xaim xaim xaim thaum hloov cov kua dej los yog yaug lub cev. Nws kuj txo qhov kev pheej hmoo ntawm kev sib kis kab mob thiab muab txoj hauv kev nyab xeeb los daws cov khoom siv hluav taws xob lossis cov khoom siv biohazardous.

Kev tshem tawm cov kua dej yog sib xws nrog cov lus qhia ruaj khov thiab siv pov tseg, thiab yog cov cuab yeej nyiam tshaj plaws rau cov khoom siv ntau yam tsawg dua 5 μL. Washable taag steel cov lus qhia yog qhov zoo tagnrho rau cov ntawv thov qhov twg cov raj yuav tsum tau tho los yog qhov zoo siab pipetting yuav tsum tau. Rau qhov yooj yim tshaj plaws, xav txog lub kaw lus uas suav nrog huab cua thiab kua hloov pauv.

Dab tsi ntim thiab hom koj ua haujlwm nrog?

Xyuas kom tseeb tias lub platform tuaj yeem tswj qhov tsim nyog ntim ntim thiab cov ntawv labware (cov raj thiab cov phaj) feem ntau siv hauv koj lub chaw kuaj mob. Kuj xav txog seb automation puas yuav tso cai rau cov qauv me me thiab cov reagent ntim siv, muab cov nqi txuag nyiaj.

Koj yuav tsum xaiv dab tsi pipeting caj npab?

Cov hom tseem ceeb yog 1) qhov sib txawv channel pipettes-feem ntau 1- mus rau 8-channel-uas tuaj yeem tuav cov raj, phaj, thiab ntau lwm yam khoom siv labware; thiab 2) multichannel caj npab tsim tshwj xeeb rau kev xa mus rau ntau qhov zoo. Cov tshuab niaj hnub no tso cai rau lub taub hau los yog cov ntawv hloov pauv hloov "ntawm ya" - qhov kev xaiv zoo rau cov txheej txheem uas siv ntau yam khoom siv sib txawv, xws li cov koob ruaj khov, cov lus qhia siv pov tseg, cov cuab yeej qis qis, thiab lwm yam.

Koj puas xav tau robotic caj npabrauntxiv yooj?

Robotic gripper caj npab muab qhov yooj yim tshaj plaws los ntawm kev txav labware ncig lub lawj ua haujlwm. Cov caj npab neeg hlau uas tuaj yeem hloov lawv "ntiv tes" sai sai kom ntseeg tau qhov yooj yim tshaj plaws thiab tuav ruaj ntseg rau ob lub raj thiab cov phaj.

Yam dab tsi ntawm pipette taub yuav ua rau kom rov tsim dua tshiab?

Cov lus qhia zoo yog qhov tseem ceeb rau kev rov tsim dua tshiab thiab tuaj yeem ua los yog rhuav tshem kev ua haujlwm. Cov lus qhia pov tseg feem ntau pom tau tias yog qhov kev xaiv zoo tshaj plaws los tshem tawm cov kab mob sib kis ntawm cov qauv tshuaj lom neeg. Qee cov neeg muag khoom tam sim no tseem muab cov lus qhia tshwj xeeb uas tsis tshua muaj txiaj ntsig rau kev xa khoom ntseeg tau ntawm microliter lossis submicroliter qib uas xav tau rau cov ntawv thov xws li kev ntsuam xyuas miniaturization. Xav txog kev yuav lub automation tus neeg muag khoom tus kheej lub npe ntawm cov lus qhia pipette kom ntseeg tau tias koj tau txais txiaj ntsig zoo tshaj plaws.

Cov cuab yeej siv cov lus qhia ruaj khov tuaj yeem muaj txiaj ntsig zoo rau kev ua haujlwm tus nqi. Tsau steel koob feem ntau tuaj yeem ncav cuag hauv qab ntawm cov hlab ntsha sib sib zog nqus zoo dua li cov lus qhia pov tseg, thiab tuaj yeem tho septa. Qhov zoo tshaj plaws tsim cov taub ntxuav cov chaw nres tsheb txo qhov kev pheej hmoo ntawm kev sib kis nrog cov teeb tsa no.

Koj puas xav tau cov lus qhia uas tau lees tias tsis muaj menyuam?

Txhawm rau txo qhov kev pheej hmoo ntawm kev sib kis, tsuas yog siv cov khoom siv uas tau sau tias "sterile." Cov no yog tsim nyob rau hauv nruj tej yam kev mob thiab ua raws li kev ntim khoom thiab thauj cov qauv uas ua kom lub taub hau tsis muaj menyuam txhua txoj hauv kev mus rau lub rooj ntev zaum. Cov khoom uas sau tias "presterile" yog tsis muaj menyuam thaum lawv tawm ntawm cov chaw tsim khoom, tab sis ntsib ntau lub sijhawm rau kev sib kis tom qab.

Software tseem ceeb

Software muab lub interface nrog tus neeg teeb tsa thiab ua haujlwm ntawm qhov ntsuas, thiab nws tus qauv tsim yuav txiav txim siab seb nws yooj yim npaum li cas rau kev pab cuam thiab cuam tshuam nrog lub kaw lus los teeb tsa cov txheej txheem ua haujlwm, teeb tsa cov txheej txheem, thiab xaiv cov ntaub ntawv tuav. Nws kuj tseem muaj kev coj ncaj qha rau ntau npaum li cas kev cob qhia yuav tsum tau ua haujlwm kom ntseeg tau. Tshwj tsis yog tias koj muaj tus kws tshaj lij software hauv tsev, tsim software tsis zoo, txawm tias muaj zog npaum li cas, tuaj yeem tso koj nyob ntawm tus neeg muag khoom lossis tus kws tshaj lij sab nraud los tsim cov txheej txheem tsim kho, daws teeb meem, thiab ua kom yooj yim tshaj plaws kev hloov pauv. Hauv ntau lub chaw kuaj mob, tus neeg teb xov tooj tsis yog tus kws tshaj lij programming, thiab feem ntau IT pab pawg yuav tsis tuaj yeem koom ncaj qha nrog cov cuab yeej tswj software. Yog li ntawd, tej zaum koj yuav tau tos rau cov kws pab tswv yim sab nraud kom muaj, ua rau muaj kev cuam tshuam loj rau kev tsim khoom thiab muab cov phiaj xwm ncua sij hawm muaj kev pheej hmoo.

Cov ntsiab lus xav txog

Cov lus nug tseem ceeb uas yuav tsum tau nug thaum ntsuam xyuas cov kua tuav cov txheej txheem software suav nrog:

  • Cov neeg ua haujlwm puas tuaj yeem cuam tshuam nrog lub touchscreen rau kev ua haujlwm txhua hnub?
  • Tus neeg muag khoom puas muaj lub tsev qiv ntawv ntawm cov txheej txheem uas twb muaj lawm los ua kom yooj yim programming?
  • Dab tsi yog qhov software kev sib koom ua ke rau cov khoom siv thib peb?
  • Dab tsi yog qhov ntawm cov cuab yeej tsav tsheb lub tsev qiv ntawv muab los ntawm tus neeg muag khoom?
  • Puas yog tus neeg muag khoom tau ntsib nrog LIMS kev cuam tshuam?
  • Koj puas yuav yooj yim programming koj tus kheej?
  • Nws yooj yim npaum li cas rau cov neeg ua haujlwm teeb tsa lawv cov kev khiav haujlwm yam tsis muaj kev tshaj lij programming?
  • Dab tsi nta - xws li customizable graphical loading guides - koj puas xav tau, thiab lawv puas muaj?
  • Puas yog nws yooj yim rau reconfigure lub software thaum lub kaw lus repurposed?
  • Tus neeg muag khoom puas tuaj yeem pab kom muaj kev ruaj ntseg cybersecurity?

Qauv traceability

Tag nrho cov qauv traceability tuaj yeem yog qhov tseem ceeb rau kev ua raws li cov qauv zoo thiab cov lus qhia. Barcode labeling, ua ke nrog cov software tsim nyog, yuav ua kom yooj yim rau kev taug qab ntawm ob qho tib si cov qauv thiab cov khoom siv, thiab tuaj yeem tiv thaiv kev ploj ntawm kev taug qab. Automated labeling thiab nrhiav kev daws teeb meem kuj tuaj yeem:

  • Qhia qhov chaw ntawm labware ntawm lub lawj thiab hauv cov chaw cia khoom
  • Xyuas kom meej tias cov ntawv cim barcode raug siv kom raug thiab tuaj yeem nyeem tau raug
  • Ua kom nrawm nrawm nyeem ntawv barcode thiab qauv xaiv cov txheej txheem, thiab ua kom muaj kev sib koom ua ke ntawm cov khoom nruab nrab thiab LIMS.

Qhov kev xaiv los cuam tshuam

Ua yuam kev yooj yim, tab sis tsis yog ib txwm yooj yim kho. Ntau lub tshuab automation tsis muaj "pib / nres" lossis "undo" ua haujlwm, uas txhais tau tias yuav tsum tau rov pib dua ib qho kev pab cuam yog tias koj nkag mus rau qee yam tsis raug lossis xav tau ncua ib txoj haujlwm. Nrhiav lub tshuab automation ntse uas tuaj yeem ntes, nkag siab, tshaj tawm, thiab rov qab los ntawm qhov yuam kev, nrog kev pib / nres ua haujlwm kom tso cai rau tus neeg teb xov tooj muaj kev nyab xeeb thiab yooj yim cuam tshuam nrog thaj chaw ua haujlwm ntawm qhov ntsuas thaum khiav.

Cov ntsiab lus

Kev tswj cov kua dej tsis siv neeg tuaj yeem tshem tawm ntau yam haujlwm nyuaj, txhim kho kev tsim khoom thiab tso lub sijhawm muaj txiaj ntsig rau kev ua haujlwm tseem ceeb dua - tab sis tsuas yog tias koj siv cov kev daws teeb meem zoo. Ua tib zoo xav txog cov ntsiab lus uas tau tham hauv tsab xov xwm no yuav pab cov chaw soj ntsuam xaiv kom zoo, cia lawv sau cov txiaj ntsig ntawm kev tuav cov kua dej thiab ua kom lub neej yooj yim dua thiab ua tau zoo dua.

 

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Post lub sij hawm: May-10-2022