ʻO ka piko pipette haʻahaʻa he liʻiliʻi, haʻahaʻa, a koʻikoʻi loa i ka ʻepekema. Manaʻo ia i ka noiʻi ʻana i nā lāʻau lapaʻau hou, nā diagnostics Covid-19, a me kēlā me kēia hoʻāʻo koko e holo mau ana.
ʻO ia hoʻi, maʻamau, nui - hiki i kahi ʻepekema pae maʻamau ke hopu i nā haneli i kēlā me kēia lā.
Akā i kēia manawa, ua hoʻokumu ʻia kahi ʻano o ka wā ʻole ma ke kaulahao hāʻawi pipette tip - i hoʻoulu ʻia e nā ʻeleʻele, nā ahi, a me nā koi e pili ana i ka maʻi maʻi maʻi - ua hana i kahi hemahema honua e hoʻoweliweli nei i nā kihi āpau o ka honua ʻepekema.
Ke hoʻoweliweli nei ka hemahema o ka pipette i nā papahana ma ka ʻāina e nānā i nā pēpē hānau hou no nā kūlana make, e like me ka hiki ʻole ke hoʻoheheʻe i nā kō i ka waiū umauma. Ke hoʻoweliweli nei ia i nā hoʻokolohua o nā kulanui e pili ana i ka genetic cell stem. A ke koi nei ia i nā ʻoihana biotech e hana ana e hoʻomohala i nā lāʻau lapaʻau hou e noʻonoʻo ai i ka hoʻokumu ʻana i kekahi mau hoʻokolohua ma mua o nā mea ʻē aʻe.
I kēia manawa, ʻaʻohe hōʻailona e pau koke ka hemahema - a inā ʻoi aku ka ʻino, pono paha e hoʻomaka ka poʻe ʻepekema e hoʻopanee i nā hoʻokolohua a haʻalele paha i nā ʻāpana o kā lākou hana.
ʻO ka poʻe ʻepekema āpau i hopohopo i ka hemahema, ʻo nā mea noiʻi kuleana no ka nānā ʻana i nā pēpē ʻoi aku ka maikaʻi loa a me ka ʻōlelo ʻole.
Nānā nā keʻena olakino olakino i nā pēpē i loko o nā hola o ko lākou hānau ʻana no ka nui o nā maʻi genetic. ʻO kekahi, e like me phenylketonuria a me MCAD deficiency, koi i nā kauka e hoʻololi koke i kā lākou mālama ʻana i ka pēpē. ʻOiai ʻo ka hoʻopaneʻe wale ʻana i ke kaʻina hoʻomaʻamaʻa ʻana ua hopena i kekahi mau keiki make, e like me ka hoʻokolokolo 2013.
Pono ka nānā ʻana o kēlā me kēia keiki ma kahi o 30 a 40 mau ʻōlelo aʻoaʻo pipette e hoʻopau ai i nā kakini o nā hoʻokolohua diagnostic, a hānau ʻia nā tausani keiki i kēlā me kēia lā ma ʻAmelika Hui Pū ʻIa.
I ka hoʻomaka ʻana o Pepeluali, ua hoʻomaopopo kēia mau labs ʻaʻole i loaʻa nā lako e pono ai lākou. ʻO nā labs ma 14 mau mokuʻāina he emi iho ma mua o hoʻokahi mahina o ka nui o nā ʻōlelo aʻoaʻo pipette i koe, e like me ka Association of Public Health Laboratories. Ua hopohopo nui ka hui, no nā mahina, ua koi ʻo ia i ke aupuni federal - me ka Hale Paʻa - e hoʻomaka i ka pono o ka pipette tip o nā papahana screening hou. I kēia manawa, ʻōlelo ka hui, ʻaʻohe mea i loli; Ua haʻi ka Hale Paʻa iā STAT e hana ana ke aupuni i nā ala he nui e hoʻonui ai i ka loaʻa o nā ʻōlelo aʻoaʻo.
I kekahi mau ʻāina, ʻo ka hapa o ka plastics ua "aneane e pani ai i nā ʻāpana o nā papahana screening hou," wahi a Susan Tanksley, he luna lālā ma ka ʻāpana lawelawe ʻoihana olakino o Texas, i ka wā o ka hālāwai Fepeluali o ke komite ʻōlelo aʻoaʻo federal no ka screening hou. . (ʻAʻole i pane aku ʻo Tankskey a me ke keʻena olakino mokuʻāina i kahi noi no ka ʻōlelo.)
Ke loaʻa nei kekahi mau mokuʻāina i nā ʻāpana o nā ʻōlelo aʻoaʻo me kahi lā i koe e waiho ai, e waiho ana iā lākou i kahi koho liʻiliʻi akā e noi aku i nā labs ʻē aʻe no ka hoʻihoʻi ʻana, e like me kā Scott Shone, ka luna o ke keʻena olakino olakino o North Carolina. Ua ʻōlelo ʻo Shone, ua lohe ʻo ia i kekahi mau luna olakino e kāhea ana "e ʻōlelo ana, 'E holo ana au i ka lā ʻapōpō, hiki iā ʻoe ke hoʻomaha i kekahi mea?' No ka mea, ʻōlelo ka mea kūʻai aku e hele mai ana, ʻaʻole wau ʻike.
"Ke hilinaʻi nei i ka ʻōlelo ʻana o kēlā mea kūʻai aku, 'ʻEkolu mau lā ma mua o kou pau ʻana, e kiʻi mākou iā ʻoe i kahi mahina ʻē aʻe' - he hopohopo," wahi āna.
Ua huli ka nui o nā labs i nā mea ʻokoʻa i hoʻopunipuni ʻia e ka jury. Ke holoi nei kekahi i nā ʻōlelo aʻoaʻo a laila hoʻohana hou iā lākou, e hoʻonui ana i ka pilikia o ka hoʻopaʻa ʻana. Ke holo nei nā poʻe ʻē aʻe i nā hōʻike hōʻike keiki hou i nā pūʻulu, hiki ke hoʻonui i ka manawa e lawe ai i nā hopena.
I kēia manawa, ua lawa kēia mau hoʻonā. "ʻAʻole mākou i kahi kūlana e pilikia koke ai nā keiki hou," i hoʻohui ai ʻo Shone.
Ma waho aʻe o nā labs e nānā ana i nā pēpē hānau hou, ʻo nā hui biotech e hana ana i nā lāʻau lapaʻau hou a me nā hale hana o ke kulanui e hana nei i ka noiʻi maʻamau.
Wahi a nā kānaka ʻepekema ma PRA Health Sciences, he hui noiʻi ʻaelike e hana nei i nā hoʻokolohua lapaʻau no ka maʻi hepa B a me kekahi mau moho lāʻau lapaʻau Bristol Myers Squibb, he mea hoʻoweliweli mau ka pau ʻana - ʻoiai ʻaʻole lākou i hoʻopaneʻe mua i nā heluhelu.
"I kekahi manawa, e iho i lalo i hoʻokahi papa o nā ʻōlelo aʻoaʻo e noho ana ma ka papa hope, a ua like mākou me 'E kuʻu mea maikaʻi'" wahi a Jason Neat, ka luna hoʻokele o nā lawelawe bioanalytical ma PRA Health's lab ma Kansas.
Ua lilo ka hemahema i mea weliweli loa ma Arrakis Therapeutics, he hui Waltham, Mass. e hana ana i na lapaau no ka ma'i kanesa, ma'i neurological, a me na ma'i laha ole, i hana ai kona poo o RNA biology, o Kathleen McGinness, i kahi ala Slack i hoolaaia e kokua i kona mau hoa hana. nā mea hoʻonā no ka mālama ʻana i nā ʻōlelo aʻoaʻo pipette.
"Ua ʻike mākou ʻaʻole kēia he koʻikoʻi," i ʻōlelo ai ʻo ia no ke kahawai, #tipsfortips. "ʻO ka hapa nui o ka hui i hana nui e pili ana i nā hoʻonā, akā ʻaʻohe o mākou wahi kikowaena e kaʻana like."
ʻO ka hapa nui o nā hui biotech i nīnau ʻia e STAT i ʻōlelo ʻia e hana ana lākou i nā hana e mālama ai i nā pipette liʻiliʻi a, a hiki i kēia manawa, ʻaʻole pono e hoʻōki i ka hana.
No ka laʻana, ke koho nui nei nā ʻepekema ʻo Octant i ka hoʻohana ʻana i nā ʻōlelo aʻoaʻo pipette kānana. ʻO kēia mau ʻōlelo aʻoaʻo - he mea paʻakikī loa ke kumu i kēia manawa - hāʻawi i nā laʻana i kahi ʻāpana pale ʻē aʻe i waho o nā mea haumia, akā ʻaʻole hiki ke hoʻomaʻemaʻe ʻia a hoʻohana hou ʻia. No laila ke hoʻolaʻa nei lākou iā lākou i nā hana koʻikoʻi paha.
"Inā ʻaʻole ʻoe e noʻonoʻo i ka mea e pau ana, hiki iā ʻoe ke holo maʻalahi i nā mea," wahi a Danielle de Jong, ka luna hoʻomalu ma ke Kulanui o Florida's Whitney Laboratory; ʻO ke keʻena hana āna i hana ai ma ke aʻo ʻana i ka hana ʻana o nā pūnaewele pū i loko o nā holoholona liʻiliʻi liʻiliʻi e pili ana i ka iʻa i hiki ke hoʻōla hou i nā ʻāpana o lākou iho.
Ua hoʻopakele nā kānaka ʻepekema ma Whitney Laboratory i ko lākou mau hoalauna ke hiki ʻole mai nā kauoha hoʻolako i ka manawa; Ua ʻike ʻo de Jong iā ia iho e nānā ana i nā papa o nā labs ʻē aʻe no nā ʻōlelo aʻoaʻo pipette i hoʻohana ʻole ʻia, inā pono kāna lab e ʻaiʻē i kekahi.
"Ua hana au ma kahi lab no 21 mau makahiki," wahi āna. "ʻAʻole au i ʻike i nā pilikia pili i nā kaulahao e like me kēia. mau loa."
ʻAʻohe wehewehe hoʻokahi no ka hemahema.
ʻO ka pahū koke ʻana o nā hōʻike Covid-19 i ka makahiki i hala - ʻo kēlā me kēia mea e hilinaʻi nei i nā ʻōlelo aʻoaʻo pipette - he mea maoli nō ia. Akā ʻo nā hopena o nā pōʻino kūlohelohe a me nā pōʻino ʻē aʻe e piʻi aʻe i luna o ke kaulahao hoʻolako i hāʻule i lalo i nā papa hana.
ʻO nā pōʻino pōʻino o ka mokuʻāina ma Texas, ka mea i make ma mua o 100 poʻe, ua uhaʻi pū kekahi i kahi loulou koʻikoʻi i ke kaulahao hoʻolako pipette paʻakikī. Ua hoʻokuʻu ʻia kēlā mau mana i ka ExxonMobil a me nā hui ʻē aʻe e pani i nā mea kanu ma ka mokuʻāina - kekahi o ia mau mea i hana i ka polypropylene resin, ka mea maka no nā ʻōlelo aʻoaʻo pipette.
Wahi a kahi hōʻike o Malaki, ʻo ExxonMobil's Houston-area mea kanu ʻo ia ka lua o ka hui nui loa o ka polypropylene i 2020; ʻO kāna mea kanu Singapore wale nō i hana hou aku. ʻElua o nā mea kanu polyethylene nui a ExxonMobil ʻekolu i loaʻa ma Texas. (I ʻApelila 2020, ua hoʻonui ʻo ExxonMobil i ka hana polypropylene ma ʻelua mau mea kanu ma US.)
"Ma hope o ka ʻino o ka hoʻoilo i Pepeluali i kēia makahiki, ua manaʻo ʻia ʻoi aku ma mua o 85% o ka mana hana polypropylene ma US i hoʻopilikia maikaʻi ʻia ma muli o nā pilikia like ʻole e like me ka haki ʻana o nā paipu i nā mea kanu hana a me ka nalowale o ka uila a nā mea waiwai nui e pono ai e hoʻomaka hou i ka hana ʻana, "wahi a ka waha ʻōlelo no Total, kahi hui aila a me ka ʻea i hoʻokumu ʻia ma Houston e hana ana i ka polypropylene.
Akā ua koʻikoʻi nā kaulahao hoʻolako mai ke kauwela i hala - ma mua o ka maloʻo hohonu o Pepeluali. ʻAʻole ʻo ka nui haʻahaʻa o nā mea maka ma mua o ka mea maʻamau ke kumu e hoʻopaʻa nei i nā kaulahao lako - a ʻo nā ʻōlelo aʻoaʻo pipette ʻaʻole ʻo ia wale nō ka ʻāpana i hoʻopaʻa ʻia i ka plastik i ka pōkole.
Ua hoʻopau pū kekahi hale hana hale hana i ka 80% o ka hoʻolako ʻana o ka ʻāina i nā ipu no nā ʻōlelo pipette i hoʻohana ʻia a me nā mea ʻoi ʻē aʻe, e like me ka palapala i kau ʻia ma ka pūnaewele o ke Kulanui o Pittsburgh.
A i Iulai, ua hoʻomaka ʻo US Customs and Border Protection i ka pale ʻana i nā huahana mai kahi mea hana mīkina lima nui i manaʻo ʻia he hana hoʻoikaika. (Ua hoʻopuka ʻo CBP i nā ʻike o kāna hoʻokolokolo i ka mahina i hala.)
"ʻO ka mea a mākou e ʻike nei he mea maoli nō ia ma ka ʻaoʻao pili i ka plastics o ka ʻoihana - polypropylene, kikoʻī - aia ma ka backorder, a i ʻole ke koi nui," wahi a PRA Health Sciences 'Neat.
He kiʻekiʻe loa ke koi no ka piʻi ʻana o ke kumukūʻai o kekahi mau lako liʻiliʻi, e like me ka Tiffany Harmon, he luna hoʻomalu kūʻai ma PRA Health Sciences 'bioanalytics lab ma Kansas.
Ke uku nei ka hui i 300% hou aku no nā mīkina lima ma o kāna mea hoʻolako maʻamau. A i kēia manawa ua uku hou ʻia nā kauoha pipette tip a PRA. ʻO kekahi mea hana pipette tip, ka mea i hoʻolaha i kahi uku hou he 4.75% i ka mahina i hala aku nei, ua haʻi aku i kāna mau mea kūʻai aku he pono ka neʻe ʻana no ka mea ua aneane pālua ke kumukūʻai o nā mea palaka maka.
ʻO ka hoʻohui ʻana i ka maopopo ʻole o ka poʻe ʻepekema ʻepekema ʻo ia ke kaʻina hana o nā mea hoʻolaha no ka hoʻoholo ʻana i nā kauoha e hoʻopiha mua ʻia - nā hana a nā mea ʻepekema liʻiliʻi i ʻōlelo ʻia ua maopopo loa iā lākou.
"Ke noi nei ke kaiāulu lab mai ka hoʻomaka ʻana e kōkua iā mākou e hoʻomaopopo i ke ʻano o kēia mau hoʻoholo ʻana," wahi a Shone, ka mea i ʻōlelo i nā ʻōkuhi o nā mea kūʻai aku no ka hoʻoholo ʻana i nā haʻawina ʻo "black box magic."
Ua hoʻokaʻaʻike aku ʻo STAT ma mua o ka ʻumi mau hui e hana a kūʻai aku i nā ʻōlelo aʻoaʻo pipette, me Corning, Eppendorf, Fisher Scientific, VWR, a me Rainin. ʻElua wale nō i pane.
Ua hōʻole ʻo Corning i ka ʻōlelo ʻana, me ka haʻi ʻana i nā kuʻikahi proprietary me kāna mau mea kūʻai. ʻO MilliporeSigma, ʻo ia hoʻi, ua ʻōlelo ʻo ia e hoʻokaʻawale i nā pipette ma ke kumu hele mua, lawelawe mua.
"Mai ka puka ʻana o ka maʻi maʻi, ua ʻike ka ʻoihana ʻepekema ola holoʻokoʻa i ke koi ʻole ʻia no nā huahana pili Covid-19, me MilliporeSigma," i haʻi aku ai kahi ʻōlelo no ka ʻoihana hoʻolaha ʻepekema nui i STAT ma kahi leka uila. "Ke hana nei mākou i ka 24/7 e hoʻokō i kēia koi nui no kēia mau huahana a me nā mea i hoʻohana ʻia i ka ʻike ʻepekema."
ʻOiai ka hoʻāʻo ʻana e hoʻoikaika i ke kaulahao lako, ʻaʻole maopopo ka lōʻihi o ka pau ʻana o nā hemahema.
Ua loaʻa iā Corning he $15 miliona mai ke Keʻena ʻOihana e hana i 684 miliona mau ʻōlelo aʻoaʻo pipette i kēlā me kēia makahiki ma kāna hale ma Durham, NC Tecan, ke kūkulu nei hoʻi i nā hale hana hou me $32 miliona mai ka CARES Act.
Akā ʻaʻole ia e hoʻoponopono i ka pilikia inā haʻahaʻa ka hana plastics ma mua o ka mea i manaʻo ʻia. A ʻaʻole hiki i kēlā mau papahana ke hana i nā ʻōlelo aʻoaʻo pipette ma mua o ka hāʻule ʻana o 2021.
A hiki i kēlā manawa, ke mākaukau nei nā luna hoʻokolohua a me nā ʻepekema no ka hemahema o nā pipette a me nā mea ʻē aʻe.
"Ua hoʻomaka mākou i kēia maʻi maʻi pōkole o ka swabs a me ka media. A laila ua nele mākou i nā reagents. A laila ua nele mākou i nā plastics. A laila ua nele hou mākou i nā reagents, "wahi a North Carolina's Shone. "Ua like ia me ka lā Groundhog."
Ka manawa hoʻouna: Feb-12-2022